RHYTHM PHARMACEUTICALS, INC.;CHARITÉ - UNIVERSITÄTSMEDIZIN BERLIN
发明人:
Leonardus H.T. Van Der Ploeg,Bart Henderson,Peter Kuhnen
申请号:
US15764725
公开号:
US20180311309A1
申请日:
2016.09.29
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The disclosure is related to a method of treating a disorder, such as Prader Willi Syndrome (PWS), obesity or hyperphagia, in a subject using a melanocortin-4 receptor (MC4R) agonist. Also described is method of treating a subject having a deficiency in the pro-opiomelanocortin (POMC)-MC4R pathway, such as a POMC-null or a PCSK-null subject, using a MC4R agonist.