A complex comprising at least one lactoferrin and at least one silica having a specific surface area comprised between 100 m2/g and 1000 m2/g (BET area, measured according to standard ISO 9277-2010), said complex being obtainable by adding said lactoferrin to said silica in the form of a sol-gel with an aqueous solvent, and subsequent drying of the sol-gel. The complex is particularly suitable for use in oral care products, in particular toothpastes, mouthwashes, gels, chewing gum, tablets for use in oral care, gingival dyes, and the like. The complex features a high level of stability and bio-availability, such that it has an effective, long-lasting antibacterial and antioxidant action within the oral cavity. The complex is particularly suitable for the prevention or treatment of diseases of dental apparatus, in particular for the prevention or treatment of periodontitis or peri- implantitis, preferably in patients suffering from diabetes.
