AMY L. CONDER,ANGELA P. TAYLOR,BONNY RENE SHAW,JEFFERY J. SEYER
申请号:
BRPI1010748
公开号:
BRPI1010748A2
申请日:
2010.06.21
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
Sodium ibuprofen compositions and methods of manufacturing tablets and caplets comprising sodium ibuprofen are described. The formulation is advantageous because it allows for the formation of tablets having low sodium content and further provides tablets exhibiting improved physical stability, high tablet hardness and high strength, coupled with excellent dissolution and bioavailability characteristics. The formulations and processes are further advantageous because they can be produced in large quantities without an unacceptable number of defective tablets.