Sarah Stoll,Julie Mertzman,Edward Van Keuren,Christopher Albanese,Stanley Fricke
申请号:
US13125244
公开号:
US09555134B2
申请日:
2009.10.21
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Nanoparticles for use as magnetic resonance imaging contrast agents are described. The nanoparticles are made up of a polymeric support and a manganese-oxo or manganses-iron-oxo cluster having magnetic properties suitable of a contrast agent. The manganese-oxo clusters may be Mn-12 clusters, which have known characteristics of a single molecule magnet. The polymer support may form a core particle which is coated by the clusters, or the clusters may be dispersed within the polymeric agent.