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PHARMACEUTICAL COMPOSITION AND PROCESS FOR THEIR PREPARATION
专利权人:
发明人:
GEORGE SHLIEOUT,BERND BOEDECKER,SIEGFRIED SCHAEFER,BERND THUMBECK,PETER-COLIN GREGORY
申请号:
IN5334/DELNP/2006
公开号:
IN251863B
申请日:
2006.09.14
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
The present invention relates to a pharmaceutical composition for oral administration, which is self-emulsifiable on contact with a hydrophilic phase and a lipophilic phase, said composition comprising: (i) enzymes or enzyme mixtures with at least lipolytic activity, and (ii) a system comprising • at least one surfactant in an amount of 2 to 90% by weight, • at least one co-surfactant in an amount of 5 to 60% by weight • in an amount of 0 to 70% by weight, a lipophilic phase represented by di- and/or triacylglycerides with aliphatic C6-C22 carboxylic acids, whereby the components surfactant, co-surfactant and the lipophilic phase together make up to 100% by weight of the system, and the system makes up 10% to 95% by weight of the pharmaceutical composition. The present invention also relates to the process for the preparation of solid pharmaceutical preparations.
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