The present invention is a therapeutic agent for treating and / or preventing diseases related to cells expressing CLD18, including tumor-related diseases including gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, liver cancer, head and neck cancer, and gallbladder cancer. As a useful antibody.본 발명은 위암, 식도암, 췌장암, 폐암, 난소암, 대장암, 간암, 두경부암, 및 담낭암을 비롯한 종양관련 질병을 함유하는, CLD18을 발현하는 세포와 관련된 질병을 치료 및/또는 예방하기 위한 치료제로써 유용한 항체를 제공한다.
