Jong Bae Park,Seung Hoon Lee,Hee Jin Kwak,Tae Hoon Kim,Heon Yoo,Donghee Lee,Eun Kyoung Park,Hea Jin Kim
申请号：
US12599735
公开号：
US08883751B2
申请日:
2008.07.30
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Disclosed is a radiation sensitivity-enhancing composition in which a microRNA-21 inhibitor acts as an active ingredient. The microRNA-21 inhibitor is an antisense nucleic acid molecule binding complementarily to microRNA-21. The composition can be administered to a patient in conjunction with irradiation. The inhibitor can act as a radiosensitizer, enhancing the therapeutic effect of such irradiation on cancer high in microRNA-21 expression level, particularly, glioma.
