A compound represented by the following formula (I), or salt thereof exhibits excellent CRF receptor antagonism, and sufficient pharmacological activity, safety and pharmacokinetic properties as a drug. (see formula I) wherein R1 represents the formula -A11-A12； R2 represents tetrahydrofurylmethyl, tetrahydropyranylmethyl or tetrahydropyranyl； represents a single bond, methylene or 1,2-ethylene； A12 represents C1-6 alkyl, C3-6 cycloalkyl or C3-6 cycloalkyl having methyl； R3 represents methoxy, cyano, cyclobutyloxymethyl, methoxymethyl or ethoxymethyl； and R4 represents methoxy or chlorine.
