An adhesive preparation comprising a stretchable support and anadhesive layer laminated on at least one side of the support, whereinthe stretchable support comprises a interlock woven fabricsubjected to crimping processing,the adhesive layer contains 10% by mass or more of methylsalicylate with respect to the total mass of the layer,the whole adhesive preparation has moisture permeability of 1 to350 g/m2.cndot.24 hr measured at a temperature of 40°C and a relativehumidity of 90%, andthe methyl salicylate has a plasma AUC0-24 ranging from 3.0 to60.0 ng.cndot.hr/mL in terms of a mean standard deviation, and salicylicacid as a metabolite of the methyl salicylate has a plasma AUC0-24ranging from 5000 to 13000 ng.cndot.hr/mL in terms of a mean standarddeviation, when the adhesive preparation is applied to a human skin for8 hours such that an application amount of the adhesive layer applied is50 to 300 g/m2 and a contact area is 280 cm2.
