YOUNG, DAVID S. F.,FINDLAY, HELEN P.,HAHN, SUSAN E.,POPP, LISA A.
申请号：
HK10104916.1
公开号：
HK1137037B
申请日:
2010.05.19
申请国别(地区):
HK
年份:
2013
代理人:
摘要：
The present invention relates to a method for producing cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, cytokines, interferons, target or reporter moieties and hematogenous cells.
