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composition and use of a long-acting oral endoparasiticide bioadhesive gel based on doramectin
专利权人:
AGROVET MARKET S.A.
发明人:
EDGAR RÉGULO VEGA CARRASCO,JORGE FABIÁN RUIZ HERRERA,JOSÉ FERNANDO TANG PLOOG,UMBERTO CALDERON OJEDA
申请号:
BRPI0913753
公开号:
BRPI0913753A2
申请日:
2009.08.28
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
The present invention relates to the composition of an oral bioadhesive endoparasiticide gel based on doramectin, having a high degree of adhesion to equine oral mucosa and having a sweet flavour greatly facilitating the dosing thereof, procedures for the preparation and the utilisation thereof. Gastrointestinal helminthosis is a parasitic condition caused by nematodes of diverse families occassioning serious gastrointestinal disorders in equine livestock. Control of this illness is of great importance and advantageously achievable through the employment of appropiate antihelmintic agents such as doramectin, being is a chemical compound widely administered by parenteral 1 route and infrequently by oral route in liquid form due to the organoleptic and physicochemical characteristics of the compositions known up to the present. The present invention demonstrates that it is possible to administer doramectin in the pharmaceutical form of an oral gel at concentrations of up to 5.0% weight/volume, overcoming the organoleptic and physicochemical restrictions of the compositions known up to the present.
来源网站:
中国工程科技知识中心
来源网址:
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