The present disclosure relates to a tooth cleaning device having an internal fluid conduit 58 formed therein, and the tooth cleaning device includes: a main body 10 which has a tube T1 provided in the main body 10 and selectively connectable with a drive unit 100; and a cleaning body 50 which is assembled to one side of the main body 10, and has the internal fluid conduit 58 formed in the cleaning body 50 and connectable with the tube T1, in which at least one nozzle 65 is formed to be opened at one end of the internal fluid conduit 58. Further, when the main body 10 and the cleaning body 50 are assembled, one end of the tube T1 is connected to one end of the internal fluid conduit 58 so as to form a single continuous flow path, and through the single continuous flow path, a cleaning solution may be discharged or a fluid is sucked and then discharged to the outside. According to the present disclosure as described above, the main body 10 and the cleaning body 50, which constitute the tooth cleaning device, may be assembled and disassembled, and as a result, it is possible to repair, replace, or wash some components such as the tube T1 and the internal fluid conduit 58 by disassembling the components.