A tooth cleaning device having an internal fluid conduit formed therein, and the tooth cleaning device includes: a main body which has a tube provided in the main body and selectively connectable with a drive unit; and a cleaning body which is assembled to one side of the main body, and has the internal fluid conduit formed in the cleaning body and connectable with the tube, in which at least one nozzle is formed to be opened at one end of the internal fluid conduit. Further, when the main body and the cleaning body are assembled, one end of the tube is connected to one end of the internal fluid conduit so as to form a single continuous flow path, and through the single continuous flow path, a cleaning solution may be discharged or a fluid is sucked and then discharged to the outside.