Grossman, William J.,Antonysamy, Mary A.,Walsh, Richard M.,Nelson, Mariana I.,Bose, Nandita,Danielson, Michael E.,Michel, Kyle S.
申请号：
AU2013257141
公开号：
AU2013257141A1
申请日:
2013.03.14
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
This disclosure describes, in one aspect, a composition that includes a β-glucan component and an antibody component that specifically binds to the β-glucan. In another aspect, this disclosure describes a method of increasing a subject's response to β-glucan immunotherapy. Generally, the method includes identifying the subject as a low binder of β-glucan and administering to the subject a composition that comprises a β-glucan moiety conjugated to the therapeutic antibody. In some cases, the therapeutic antibody can be an anti-tumor antibody.
