A device for deriving electrical signals or for electrically simulating neuronal tissue. Neuroelectrodes form an interface between the biological tissue and technical systems. Existing neuroelectrodes for contacting low-lying neuronal layers diminish their properties by the interaction with biological tissue. In order to improve the long-time behavior, neuroelectrodes filled with bioactive substances are used. The neuroelectrode is formed on a flexible or rigid substrate with the aid of a line and of a microcapillary. The inside of the microcapillary serves as a container for the bioactive substance. The biostable neuroelectrode is used for deriving electrical signals or for electrically stimulating neuronal tissue in the fields of neurology and neurophysiology.