BOSCH, H. William,CALLAHAN, Matthew,MEISER, Felix,NORRET, Marck,RUSSELL, Adrian
申请号:
AU2016202881
公开号:
AU2016202881A1
申请日:
2016.05.04
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
#$%^&*AU2016202881A120160526.pdf#####ABSTRACT Methods for making inhalable composite particles comprising a pharmaceutically-active agent, the method comprising: a) providing composite particles comprising a millable grinding matrix and a solid pharmaceutically-active agent, wherein the pharmaceuticallyactive agent has an median particle size on a volume average basis between 50 nm and 3 pm; and b) milling the composite particles in a mill without milling bodies for a time period sufficient to produce inhalable composite particles having a mass median aerodynamic diameter between 1 pm and 20 pm are described.WO 2013/128283 PCT/IB2013/000708 1/2 FIGURE 1