The composite moisture-proof medicine box comprises: a chassis, which is provided with a first holding space connected with the outside, one side of the chassis is pivoted with a fastener, and a first convex rib is arranged on the top ring of the chassis.And a first cover body, one end of which is pivotally combined with the chassis other than the end with the fastener, the bottom edge of the first cover body is provided with a groove to accommodate an elastic element. When the first cover body pivots to contact with the top edge of the chassis, one end of the elastic element is against the first rib, and then the fastener is buckled on the first cover body to make the chassis and the first rib. A cover body is air tight.本創作複合式防潮藥盒，其包括有：一底盤，其係具有一與外部連通之第一容置空間，該底盤之一側樞設有一扣件，且該底盤之頂緣上環設有一第一凸肋。以及一第一蓋體，其一端係與該底盤異於設有該扣件之一端樞設結合，該第一蓋體之底緣設有一凹槽，提供容設一彈性元件，當該第一蓋體樞轉而與該底盤之頂緣接觸時，該彈性元件之一端則抵靠於該第一凸肋上，再以該扣件扣合於該第一蓋體上，使該底盤及該第一蓋體氣密結合。
