GATTI, PAOLO,COLOMBO, ITALO,GERVASONI, DARIO,PIRONTI, VINCENZA,ALBORGHETTI, LIA,FABIANI, FLAVIO,BOLTRI, LUIGI
申请号：
CA2820437
公开号：
CA2820437A1
申请日:
2011.12.22
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The invention provides a composite of drug, polymeric carrier and at least one not cross linked polymer useful to improve the solubility of poorly water soluble drugs. The present invention comprises manufacturing process of this composite material. The manufacturing process is carried out by the solvent induced activation process, wherein the not cross-linked polymer is loaded into the composite from organic solution, possibly together with the drug. Pharmaceutical compositions comprising said composite in combination with pharmaceutical acceptable excipients are also described herein.
