KIM, Sooyeon;김호현;주식회사 한국의약연구소;정지훈;KOREA MEDICINE RESEARCH INSTITUTE, INC;KOREA MEDICINE RESEARCH INSTITUTE;JEONG, Ji Hoon;KIM, Hohyun;김수연; INC
发明人:
JEONG, Ji Hoon,정지훈,KIM, Hohyun,김호현,KIM, Sooyeon,김수연
申请号：
KRKR2015/003691
公开号：
WO2015/190682A1
申请日:
2015.04.14
申请国别(地区):
KR
年份:
2015
代理人:
摘要：
The present invention relates to a growth promotion effect of coumaric acid and, more specifically, to a pharmaceutical composition, a food composition, and an animal feed composition, which are for growth promotion and contain coumaric acid as an active ingredient. The composition containing coumaric acid as an active ingredient, of the present invention, promotes chondrocyte proliferation and growth hormone secretion, thereby finally having an effect of promoting growth, and thus the composition of the present invention is effective in not only growth and skeletal formation of growing children and adolescents, but also height growth therapy by being used alone or in combination with growth hormone therapy.La présente invention concerne l'effet de promotion de la croissance de l'acide coumarique et, plus spécifiquement, une composition pharmaceutique, une composition alimentaire et une composition alimentaire pour animaux, qui sont destinés à promouvoir la croissance et contiennent de l'acide coumarique comme principe actif. La composition de la présente invention contenant de l'acide coumarique comme principe actif favorise la prolifération des chondrocytes et la sécrétion de l'hormone de croissance, ce qui finalement a pour effet de promouvoir la croissance. La composition de la présente invention est donc efficace non seulement pour développer et former le squelette des enfants et des adolescents en pleine croissance, mais aussi pour le traitement de croissance en hauteur en étant utilisée seule ou en association avec un traitement par hormones de croissance.본 발명은 쿠마린산 (Coumaric add)의 성장 촉진 효과에 관한 것으로, 더욱 상세하게는 쿠마린산을 유효성분으로 포함하는 성장 촉진용 약학적 조성물, 식품 조성물 및 동물 사료용 조성물에 관한 것이다. 본 발명의 쿠마린산을 유효성분으로 포함하는 조성물은 연골세포의 세포 증식과 성장호르몬 분비를 촉진시켜 결론적으로 성장을 촉진시키는 효과가 있어, 성장기의 유소아 및 청소년의 성장 및 골격을 형성하는데 효과적일뿐만 아니라 본 발명의 조성물 단독으로 또는 성장호르몬 치료와 병행요법을 통해 키 성장 치료에 효과적이다.
