Chi Ming Che,Raymond Wai-Yin Sun,Lok Fung Chow,Jing Yan
申请号：
US12913395
公开号：
US08530659B2
申请日:
2010.10.27
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present disclosure is related to a pharmaceutical composition for treatment of cancer comprising a cyclometalated N-heterocyclic carbene complex. The cyclometalated N-heterocyclic carbene complex contains a gold(III) or a platinum(II) atom. The pharmaceutical composition possesses anti-cancer activity such as the induction of cell death, inhibition of cellular proliferation, inhibition of topoisomerase and/or poisoning of topoisomerase.
