CHE, CHIMING,SUN, WAIYIN, RAYMOND,CHOW, LOKFUNG,YAN, JING
申请号:
EP10825938
公开号:
EP2493896A4
申请日:
2010.10.27
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The present disclosure is related to a pharmaceutical composition for treatment of cancer comprising a cyclometalated N-heterocyclic carbene complex. The cyclometalated N-heterocyclic carbene complex contains a gold(III) or a platinum(II) atom. The pharmaceutical composition possesses anti-cancer activity such as the induction of cell death, inhibition of cellular proliferation, inhibition of topoisomerase and/or poisoning of topoisomerase.