OTSUKA PHARMACEUTICAL CO., LTD.;JUNTENDO UNIVERSITY
发明人:
ARAI, HEII,新井平伊
申请号：
TW102147146
公开号：
TWI489983B
申请日:
2008.05.21
申请国别(地区):
TW
年份:
2015
代理人:
摘要：
The invention relates to a medicament for treating Alzheimer's disease comprising as active ingredients a carbostyril derivative of the general formula:wherein A is a lower alkylene group, R is a cycloalkyl group, the bonding between 3- and 4-positions of the carbostyril skeleton is a single bond or a double bond, or a salt thereof； and donepezil or a salt thereof.本發明係關於一種用於治療阿茲海默症之藥劑，包括以下各者作為活性成分：通式(1)之喹諾酮(carbostyril)衍生物或其鹽[式中，A為低級伸烷基；R為環烷基；喹諾酮骨架之3及4位置間的鍵結為單鍵或雙鍵]；以及冬尼培唑(donepezil)或其鹽。
