EBENS JR ALLEN J.,SPENCER SUSAN D.,JACOBSON FREDERIC S.,POLAKIS PAUL,SCHWALL RALPH H.,SLIWKOWSKI MARK X
申请号：
IN7052/DELNP/2006
公开号：
IN256066B
申请日:
2006.11.23
申请国别(地区):
IN
年份:
2013
代理人:
摘要：
The present invention relates to antibody-drug conjugate compounds of Formula I: where one or more maytansinoid drug moieties (D) are covalently linked by L to an antibody (Ab) which binds to an ErbB receptor, or which binds to one or more tumor-associated antigens or cell-surface receptors. These compounds may be used in methods of diagnosis or treatment of cancer, and other diseases and disorders.
