LI , YOUXIN,WANG, AIPING,LIU, WANHUI,SUN, KAOXIANG,LI , JUN,SUN, LIFANG
申请号:
CA2816288
公开号:
CA2816288C
申请日:
2011.11.25
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The disclosure provides a composition comprising rotigotine or a pharmaceutically acceptable salt thereof; at least one poly(lactide-co-glycolide) (PLGA); and at least one fatty acid, wherein the at least one fatty acid is at least 0.5% in weight relative to the total weight of the composition. The composition as disclosed herein has significantly reduced burse release effect. The disclosure also provides a method of treating Parkinson's disease comprising administering an effective amount of the composition as disclosed to a subject in need thereof.