Peter Bernard HEIFETZ,Blanca LLOMPART ROYO,Pablo MARZÁBAL LUNA,Miriam BASTIDA VIRGILI,Maria Dolores LUDEVID MÚGICA,Margarita TORRENT QUETGLAS,Kevin James OCONNER,Roser Pallisse BERGWERF,Maria Immacula
申请号:
US14721478
公开号:
US20150335720A1
申请日:
2015.05.26
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A fusion protein that is expressed in a recombinant protein body-like assembly (RPBLA) in host eukaryotic cells and organisms is disclosed. More particularly, a biologically active polypeptide fused to a protein sequence that mediates the induction of RPBLA formation is expressed and accumulated in host cells after transformation with an appropriate vector. The eukaryotic host cell does not produce protein bodies in the absence of the fusion protein. Methods for preparing and using the RPBLAs and the fusion protein are also disclosed, as are nucleic acid molecules that encode the fusion proteins.