The method of this invention for the prevention and treatment of the novel azole of formula 1A and 1B, the novel antiviral active ingredient, the pharmaceutical composition, an antiviral drug, in particular viral diseases caused by the hepatitis C virus (HCV) in It relates. Wherein: a solid line (---) accompanying the dotted line is one of them represents a single bond or a double bond, a single bond and the other is a double bondX and Y are one of which is nitrogen (N), the other is oxygen (O), sulfur (S) or -NH groupR1 AndR2 is 2- (R) - and (S) - substituted N- acyl pyrrolidine derivatives N- methyl -N- [2- (R) and (S) - substituted 2,2-disubstituted acetamide Methyl [2- (R) and (S) - substituted ((methyl) amino) - (1-oxo-butane-2-yl) -2- (R) -] and (S) - iso-propyl) carbazole It is optionally the same radical selected from formate.A is Dioxane, cycloalkyl-and bicyclo aliphatic, alkyloxy-alkyl, alkyloxy-alkylene-oxy-alkyl, alkenyloxy-alkyl, alkynyloxy-alkyl radical of bi and its thio analog Acyl and thiophene-alkynyl cycloalkyl, alkynyl dioxane, alkynyl, aryl, alkyl-thiophene, alkenyl nilti thiophene and alkynyl nilti thiophene, alkyloxy aryl, alkenyloxy aryl, alkynyloxy aryl, alkylthio aryl, alkenyl thio aryl, alkynyl, aryl thio, cycloalkyl thiophene, an aliphatic C 2 -C 8 by a radical of aryl-dioxane and thiophenyl dioxane It shows a bi-radical.B is an acyl and thiophene, alkynyl, cycloalkyl, alkynyl dioxane, alkynyl, aryl, alkyl-thiophene, thiophene nilti alkenyl and alkynyl nilti thiophene, cycloalkyl benzene, 4-bi-phenyl-cycloalkyl, bicyclic cycloalkyl, benzene, 4- by bi-cycloalkyl, phenyl, cycloalkyl, thiophene, acyl dioxane and dioxane thiophenyl radical a single, double or triple bonds, including aliphatic C 2 -C 8 It represents a radical.본 발명은 신규한 아졸, 화학식 1A 및 1B의 신규한 항바이러스 활성 성분, 약학적 조성물, 항바이러스 약물, 특히 C형 간염 바이러스(HCV)에 의해 발병하는 바이러스성 질환의 예방 및 치료를 위한 방법에 관한 것이다.여기서: 점선을 수반하는 실선(---)은 단일 결합 또는 이중 결합을 나타내며, 이들 중 하나가 단일 결합이면, 다른 하나는 이중 결합이고 X 및 Y는 이들 중 하나가 질소(
