GEORGE DAVIS,WILLIAM LO,JAMES RENGA,FRANCIS TISDELL,MAURICE YAP,DAVID YOUNG
申请号:
IN8754/DELNP/2011
公开号:
IN2011DN08754A
申请日:
2011.11.11
申请国别(地区):
IN
年份:
2013
代理人:
摘要:
Various aspects disclosed herein relate to aryl substituted aminopyrimidines according to Formula (I), wherein, X1 is N or C-R3 X2 is N or C-R, provided that X1 and X2 are not both N R1-R7 are H, CN, CHO, -SCN, NO2, F, C1, Br, I, substituted or unsubstituted C1-C4-alkyl, substituted or unsubstituted halo-C1-C4-alkyl, substituted or unsubstituted C1 -C4-alkoxy, substitut-ed or unsubstituted halo-C1-C4-alkoxy, substituted or unsubstituted C1-C4-thioalkyl, substituted or unsubstituted halo-C]-C4-thioalkyl, substituted or unsubstituted C3-C-7-cycloalkyl, substituted or unsubstituted C2-C4-alkenyl, C2-C4-alkynyl, substituted or unsubstituted C1-C4-acylalkyl, C1-C4-acyloxy, C1-C4 alkoxycarbonyl, C1-C4-alkoxy-amino, C1-C4-alkyl-S(O)=NH, substi¬tuted or unsubstituted aryl, substituted or unsubstituted heterocycle, wherein the substituents are one or more of the following F, C1, Br, OH, CN, NO2, CHO, -SCN, S(O)n-C1-C4-alkyl (where n = 0-2), C1-C4-alkyI, halo-C1-C4-alkyl, C1-C4-alkylamine, C1-C4-alkoxy, halo-C1-C4-aIkoxy, C1-C4-thioalkyl, halo-C1-C4-thioalkyl, C1-C4-alkylacyl, C1-C4-acyloxy, C1-C4 alkoxycarbonyl, C1-C4-alkoxy-imino, hydroxy- imino C1-C4-alkyl-S(O)=NH and Q is a substituted or unsubstituted aryl, substituted or unsub¬stituted heterocycle wherein the substituents of Q are taken from R1-R7.