A medical electronic device comprises at least a battery module, a detector for detecting the remaining battery of the battery module to generate a detection signal, a processor generating a first status information according to the detection signal, a transceiver and a function circuit. The processor transmits and receives the first status information and the control signal by the transceiver. The function circuit is electrically connected to the processor and at least an electrode. The electrode extends outward from the medical electronic device. According to the control signal, the processor controls the function circuit to output an electrical stimulation signal with default stimulation frequency, stimulation cycle and stimulation intensity to the electrode. The voltage of the electrical stimulation signal ranges from −10V to −1V and from 1V to 10V, and the frequency of the electrical stimulation signal is between 200 KHz and 800 KHz.