An integrated manual/mechanical ventilation driving device comprising a movable or deformable internal chamber comprising a first port for air communication, the internal chamber being at least partially disposed within a movable or deformable external chamber comprising a second port for air communication, wherein when a driving gas enters a space between the external chamber and the internal chamber through the second port, the internal chamber is squeezed so that gas is expelled from the internal chamber through the first port, and wherein the external chamber is configured to be manually squeezed or deformed inwardly to contact and squeeze the internal chamber so that gas is expelled from the internal chamber through the first port.