LEE KATHERINE L,MCKEW JOHN C.,CHEN LILHREN,VARGAS RICHARD,CLARK JAMES D,WILLIAMS CARA,CLERIN VALERIE,MARUSIC SUZANA,PONG KEVIN
申请号:
IN4549/KOLNP/2007
公开号:
IN262016B
申请日:
2007.11.26
申请国别(地区):
IN
年份:
2014
代理人:
摘要:
This invention provides chemical inhibitors of the activity of various phospholipase enzymes, particularly cytosolic phospholipase A2 enzymes (cPLA2), more particularly including inhibitors of cytosolic phospholipase A2 alpha enzymes (cPLA2a). In some embodiments, the inhibitors have the Formula (I): wherein the constituent variables are as defined herein.