MCKEW, JOHN C.,LEE, KATHERINE L.,CHEN, LIHREN,VARGAS, RICHARD,CLARK, JAMES D.,WILLIAMS, CARA,CLERIN, VALERIE,MARUSIC, SUZANA,PONG, KEVIN
申请号：
CA2607857
公开号：
CA2607857C
申请日:
2006.05.26
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
This invention provides chemical inhibitors of the activity of variousphospholipase enzymes, particularly cytosolic phospholipase A2 enzymes(cPLA2), more particularly including inhibitors of cytosolic phospholipase A2alpha enzymes (cPLA.alpha.). In some embodiments, the inhibitors have theFormula I: wherein the constituent variables are as defined herein.
