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Melted tumeric extract and curcumin with high solubility in biocompatible solvents
专利权人:
发明人:
정혜선,양현옥,이정애,권학철,정준영,송영호,박주영,김지연
申请号:
KR1020110127052
公开号:
KR1014180580000B1
申请日:
2011.11.30
申请国别(地区):
KR
年份:
2014
代理人:
摘要:
PURPOSE: An amorphous turmeric extract and amorphous curcumin are provided through cooling below a melting point after heating a turmeric extract or curcumin to reach above the melting point. CONSTITUTION: An organic solvent extract of turmeric is obtained in a pure solution state by extracting turmeric with a solvent and filtering. The turmeric extract is heated at a range of 180-240 deg. C for 0.1-10 minutes, and amorphous curcumin is obtained by cooling with a temperature below 190 deg. C. A solubilization component of the turmeric extract includes an amorphous turmeric extract solution in which the amorphous turmeric extract is dissolved in a biocompatible solvent selected from one or more of a group composed of linear alcohol or branched alcohol with 1-4 carbons, poly ethylene glycol with 100-1,000 number average molecular weight, glycerol, acetic acid, and polyoxyethylene sorbitan fatty acid ester. [Reference numerals] (AA) Turmeric extract; (BB) Melted turmeric extract본 발명은 녹는점 이상으로 가열하여 녹였다가 녹는점 미만으로 식힌 강황 추출물 (tumeric extract) 또는 커큐민, 이들을 포함하는 조성물 및 제조방법에 대한 것이다. 녹인 후 식힌 강황 추출물 또는 커큐민은 무정형 (amorphous)을 이루며 결정성인 녹이지 않은 강황 추출물 또는 커큐민에 비해 생체적합성 용매인에 높은 용해도를 가진다.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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