PROBLEM TO BE SOLVED: To provide: hyaluronic acid synthesis promotor by using fractions or components obtained from Oroxylum indicum and high in safety; a HAS2 mRNA expression promotor by using fractions or components obtained from Oroxylum indicum and high in safety; a pharmaceutical, food product or cosmetic which contains hyaluronic acid synthesis promotor of the invention and has hyaluronic acid synthesis promoting action; and a pharmaceutical, food product or cosmetic which contains the HAS2 mRNA expression promotor of the invention and has HAS2 mRNA expression promoting action.SOLUTION: A hyaluronic acid synthesis promotor and HAS2 mRNA expression promotor of the invention contain: first fractions that are fractions extracted from a seed of Oroxylum indicum by aqueous organic solvent and include at least chrysin; and other fractions or chrysin obtained by refining the first fractions, as active ingredients. The invention further provides a pharmaceutical, food product or cosmetic that contains the hyaluronic acid synthesis promotor or HAS2 mRNA expression promotor of the invention.【課題】「安全性が高いソリザヤノキから得られる分画物又は成分を用いたヒアルロン酸合成促進剤」、「安全性が高いソリザヤノキから得られる分画物又は成分を用いたHAS2mRNA発現促進剤」、「本発明のヒアルロン酸合成促進剤を含有し、ヒアルロン酸合成促進作用を有する医薬品、食品又は化粧料」及び「本発明のHAS2mRNA発現促進剤を含有し、HAS2mRNA発現促進作用を有する医薬品、食品又は化粧料」を提供する。【解決手段】ソリザヤノキの種子から水性有機溶媒により抽出される分画物であって少なくともクリシンを含む第1分画物、第1分画物を精製して得られる他の分画物又はクリシンを、有効成分として含有するヒアルロン酸合成促進剤又はHAS2mRNA発現促進剤。また、本発明のヒアルロン酸合成促進剤又はHAS2mRNA発現促進剤を含有する医薬品、食品又は化粧料。【選択図】図1