LIBERATION MODIFIEE DE 4-METHYL-3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]-N-5-(4-METHYL-1H-IMIDAZOL-1-YL)-3-(TRIFLUOROMETHYL)PHENYL] BENZAMIDE SOLUBILISE A L'AIDE D'ACIDES ORGANIQUES

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专利权人:

NOVARTIS AG

发明人:

LI, SHOUFENG,KUMAR, SARAN,KAVIMANDAN, NIKHIL JAVANT,LU, ENXIAN

申请号：

CA2838741

公开号：

CA2838741A1

申请日:

2012.06.13

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

Soluble pharmaceutical compositions of amorphous nilotinib or a pharmaceutically acceptable salt thereof were invented using one or more organic acids that function as a solubilizing agent, increasing the bioavailability of nilotinib and supressing the food effect associated with certain compositions of nilotinib. The pharmaceutical compositions are in th form of solid oral dosage forms, including capsules and tablets.

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中国工程科技知识中心

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