PROBLEM TO BE SOLVED: To provide a chlorin derivative that is a photosensitive material for photodynamic therapy and has antitumor activity and a metal complex thereof.SOLUTION: This invention provides a chlorin derivative represented by the general formula (I) or a metal complex thereof, wherein R1-R20 are different or the same and represent F-, mannose-S- or the like R21 and R22 are different or the same and represent a hydrogen atom, alkyl or E-(CH2)n-, where E represents aryl, amino, alkylamino, imino or the like and n represents an integer of 0-3.COPYRIGHT: (C)2015,JPO&INPIT【課題】光線力学療法用の光感受性物質である抗腫瘍活性を有するクロリン誘導体及びその金属錯体の提供。【解決手段】一般式(I):[式中、R1~R20は、同一又は異なって、F-、マンノース-S-などを示す。R21及びR22は、同一又は異なって、水素原子、アルキル又はE-(CH2)n-を示す。ここで、Eは、アリール、アミノ、アルキルアミノ、イミノなどを示し、nは0~3の整数を示す。]で表されるクロリン誘導体又はその金属錯体。【選択図】図3
