新規ステロイド１１β水酸化酵素およびそれを用いた１１βヒドロキシステロイドの製造方法

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专利权人:

三菱化学株式会社

发明人:

小川 順,木村 隆利,依田 尚文,山本 恭士,阪本 剛

申请号：

JP20120285649

公开号：

JP6107130(B2)

申请日:

2012.12.27

申请国别(地区):

日本

年份:

2017

代理人:

摘要：

PROBLEM TO BE SOLVED: To provide a new steroid 11&bgr;-hydroxylase useful for producing a 11&bgr;-hydroxysteroid such as a hydrocortisone.SOLUTION: There is provided a protein of (a1), (b1) or (c1): (a1) a protein including a specific amino acid sequence, (b1) a protein including an amino acid sequence in which one or some amino acids are deleted, substituted or added in a specific amino acid sequence, and having steroid 11&bgr;-hydroxylation activity, (c1) a protein including an amino acid sequence with a sequence identity of not less than 90% to a specific amino acid sequence, and having steroid 11&bgr;-hydroxylation activity.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/