A composition having an immunomodulating action, comprising RNA derived from lactic acid bacteria as an active ingredient. Or the composition which has the effect action which adjusts cytokine production which uses RNA derived from lactic acid bacteria as an active ingredient.乳酸菌由来のRNAを有効成分とする、免疫調整作用を有する組成物。または乳酸菌由来のRNAを有効成分とする、サイトカイン産生を調整する作用を有する組成物。