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METHODS OF IMAGING INFLAMMATORY DISEASES BY LIGANDS CONJUGATED TO FLUORESCENT COMPOUNDS
专利权人:
PURDUE RESEARCH FOUNDATION
发明人:
LOW, PHILIP S.,KULARATNE, SUMITH A.,KELDERHOUSE, LINDSAY E.,MAHALINGAM, SAKKARAPALAYAM, M
申请号:
EP13877792
公开号:
EP2972320A4
申请日:
2013.12.19
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid or derivative thereof. The disclosure further describes methods and compositions for making and using the compounds, methods incorporating the compounds, and kits incorporating the compounds.
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