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Imaging methods of inflammatory diseases using ligands conjugated with fluorescent compounds
专利权人:
Purdue Research Foundation;Kularatne, Sumith A.;Kelderhouse, Lindsay E.;Low, Philip S.
发明人:
LOW, Philip S.,KULARATNE, Sumith A.,KELDERHOUSE, Lindsay E.,MAHALINGAM, Sakkarapalayam
申请号:
ES13877792
公开号:
ES2765896T3
申请日:
2013.12.19
申请国别(地区):
ES
年份:
2020
代理人:
摘要:
The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid or derivative thereof. The disclosure further describes methods and compositions for making and using the compounds, methods incorporating the compounds, and kits incorporating the compounds.
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