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Folate receptor 1 antibodies and immunoconjugates and uses thereof
专利权人:
IMMUNOGEN INC.
发明人:
GOLDMAKHER VIKTOR S,AB OLGA,PAYNE GILLIAN,RUI LINGYUN,TAVARES DANIEL
申请号:
NZ70939011
公开号:
NZ709390A
申请日:
2011.02.24
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
Disclosed is antibody or antigen binding fragment thereof that specifically binds a human folate receptor, wherein the antibody comprises: (a) a heavy chain (HC) CDR1 comprising the amino acid sequence of GYTFTGYFMN (SEQ ID NO:132); a HC CDR2 comprising the amino acid sequence of RIHPYDGDTF (SEQ ID NO:131); and a HC CDR3 comprising the amino acid sequence of YDGSRAMDY (SEQ ID NO:3); and (b) a light chain (LC) CDR1 comprising KASQSVSFAGTSLMH (SEQ ID NO:7); a LC CDR2 comprising RASNLEA (SEQ ID NO:8); and a LC CDR3 comprising QQSREYPYT (SEQ ID NO:9).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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