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PREPARATION D'UNE FORME SOLIDE DE GADOBENATE DE DIMEGLUMINE
专利权人:
BRACCO IMAGING SPA
发明人:
MAZZON, ROBERTA,FRETTA, ROBERTA,ANELLI, PIER LUCIO
申请号:
CA2950831
公开号:
CA2950831A1
申请日:
2015.07.20
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention relates to a process for the preparation of a solid form of the gadobenate dimeglumine compound that comprises obtaining a solution of the said compound in a suitable solvent A wherein the amount by weight of the water optionally present in the solution is at most equal to or lower than the amount by weight of the gadobenate dimeglumine comprised in the solution and adding the obtained solution to an organic solvent B, acting as an appropriate antisolvent and favoring the formation of a solid form of the gadobenate dimeglumine that can be collected by filtration.
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中国工程科技知识中心
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