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NOVEL DIAZENIUMDIOLATE DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
专利权人:
LES LABORATOIRES SERVIER
发明人:
CORDI ALEXIS,HABERKORN LAURE,VERBEUREN TONY,COURCHAY CHRISTINE,SIMONET SERGE
申请号:
NZ58607008
公开号:
NZ586070A
申请日:
2008.12.10
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed are indole compounds represented by general formula (I). An example of the compound of formula (I) is: ({ [(1Z)-2,2-diethyl-1-oxidohydrazono]amino} oxy)methyl 3-{ [({ 2-chloro-5-[(2-methyl-5-nitro-2,3-dihydro-1H-indol-I-yl)carbamoyl]phenyl} sulphonyl)amino ]methyl} benzoate. The compounds of formula (I) are used to treat hypertension and cardiovascular pathologies and complications such as retinopathy, cerebral accidents, dementia, left ventricular hypertrophy, cardiac insufficiency, angina pectoris, myocardial infarction, nephropathy, cerebral and coronary accidents, arteritis, vasculopathies, vascular complications of disorders such as diabetes, obesity, metabolic syndrome, cancer or fibrosis of the liver and for the treatment of hypertension of pulmonary, ocular or portal origin.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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