A dispenser (100) for dispensing a predetermined amount of material from a prefilled syringe (102) is provided. The dispenser includes a dispenser body (104) and a plunger (124). The dispenser body (104) includes a syringe mounting region (108) and a nozzle portion (164) through which the material is dispensed. The nozzle portion (164) has a syringe dispensing end receiving cavity (168) configured to mate with the dispensing end (118) of the syringe (102) and an outlet (172). A fluid flow path fluidly communicates the syringe dispensing end receiving cavity (168) with the outlet (172) and includes a measuring cavity (180) having a predetermined volume. The plunger (124) is carried by the dispenser body (104). The plunger (124) has a retracted state in which the plunger (124) is retracted from the measuring cavity (180) such that the outlet (172) is in fluid communication with the syringe dispensing end receiving cavity (168). The plunger (124) has a depressed state in which the plunger (124) extends through the measuring cavity (180) to evacuate material from the measuring cavity (180).