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TASTE MASKING DRUG FORMULATIONS
专利权人:
Orbis Biosciences; Inc.
发明人:
BERKLAND, Cory,SINGH, Milind
申请号:
EP15754648
公开号:
EP3110403A4
申请日:
2015.02.25
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present disclosure relates to a taste-masking microcapsule composition. The composition comprises a core portion encapsulated by a shell portion. The core portion comprises an active pharmaceutical ingredient (API) and one or more excipients. The shell portion comprises a hydrophobic matrix and a pH-responsive material. The microcapsule compositions prevent API release at the more neutral pH levels in the oral cavity, but upon exposure to pH levels of the stomach, the pH-responsive material becomes soluble thereby permitting release of the API.
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