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TASTE MASKING DRUG FORMULATIONS
专利权人:
ORBIS BIOSCIENCES; INC.
发明人:
CORY BERKLAND,MILIND SINGH
申请号:
US15244455
公开号:
US20160354317A1
申请日:
2016.08.23
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present disclosure relates to a taste-masking microcapsule composition. The composition comprises a core portion encapsulated by a shell portion. The core portion comprises an active pharmaceutical ingredient (API) and one or more excipients. The shell portion comprises a hydrophobic matrix and a pH-responsive material. The microcapsule compositions prevent API release at the more neutral pH levels in the oral cavity, but upon exposure to pH levels of the stomach, the pH-responsive material becomes soluble thereby permitting release of the API.
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