ADMINISTRATION D'INHIBITEUR D'ENZYME ACTIVANT L'UBIQUITINE ET AGENTS CHIMIOTHÉRAPEUTIQUES

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专利权人:

Inc.;Millennium Pharmaceuticals

发明人:

申请号：

EP15853752.2

公开号：

EP3212650A4

申请日:

2015.10.23

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

Disclosed are methods for the treatment of cancer in patients in need of such treatment. The methods comprise administering to such a patient an ubiquitin-activating enzyme (UAE) inhibitor such as ((1R,2R,3S,4R)-2,3-dihydroxy-4-(2-(3-(tri-fluoromethylthio)phenyl)pyrazolo [1,5-a]pyrimidin-7-ylamino)cyclopentyl)methyl sulfamate (Compound 1) or a pharmaceutically acceptable salt in combination with one or more chemotherapeutic agents. Also disclosed are medicaments for use in the treatment of cancer.

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中国工程科技知识中心

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http://www.ckcest.cn/home/