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CO-ADMINISTRATION D'UN INHIBITEUR D'ENZYME ACTIVANT L'UBIQUITINE ET DE RAYONS
专利权人:
Inc.;Millennium Pharmaceuticals
发明人:
BENCE, Neil,HYER, Marc,MILHOLLEN, Michael,SAMNOTRA, Vivek,SANTILLANA SOTO, Sergio Luis,SAPPAL, Darshan
申请号:
EP15854199
公开号:
EP3212651A4
申请日:
2015.10.23
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Disclosed are methods for the treatment of cancer in patients in need of such treatment. The methods comprise administering to such a patient an ubiquitin-activating enzyme (UAE) inhibitor such as ((1R,2R,3S,4R)-2,3-dihydroxy-4-(2-(3-(trifluoromethylthio) phenyl)pyrazolo[1,5-a]pyrimidin-7-ylamino)cyclopentyl)methyl sulfamate (Compound 1) or a pharmaceutically acceptable salt in combination with radiation. Also disclosed are medicaments for use in the treatment of cancer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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