Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
Noah Bell,Christopher Carreras,Dominique Charmot,Jeffrey W Jacobs,Michael Robert Leadbetter,Marc Navre
申请号:
US13826186
公开号:
US09006281B2
申请日:
2013.03.14
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present disclosure is directed to compounds and methods for treating irritable bowel syndrome, chronic kidney disease and end stage renal disease by administering to a subject in need thereof a compound or a pharmaceutically acceptable salt thereof, wherein the compound has the structure