Refers to a Pharmaceutical composition comprising: (a) The Compound 3 - (dimethylamino) - 1 - ethyl - 2 - Methyl Propyl phenol) in the form of one of its stereoisomers such as (1R, 2R) - 3 - (dimethylamino) - 1 - ethyl - 2 - Methyl Propyl) phenol, (1S, 2S) - 3 - (dimethylamino) - 1 - ethyl - 2 - Methyl Propyl phenol) -, (1R, 2S) - 3 - (3 - Tell Me Tilamino - 1 - ethyl - 2 - Methyl Propyl) - phenolAmong others and (b) a receptor antagonist of n-methyl-d-aspartate (NMDA) as (R, S) - ketamine, (S) - ketamine, memantine, norvaline, among others. The pharmaceutical composition is useful in the treatment of Pain and has a synergistic effectSE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE: A) EL COMPUESTO 3-(3-DIMETILAMINO-1-ETIL-2-METIL-PROPIL)-FENOL EN FORMA DE UNO DE SUS ESTEREOISOMEROS TALES COMO (1R,2R)-3-(3-DIMETILAMINO-1-ETIL-2-METIL-PROPIL)-FENOL, (1S,2S)-3-(3-DIMETILAMINO-1-ETIL-2-METIL-PROPIL)-FENOL, (1R,2S)-3-(3-DIMETILAMINO-1-ETIL-2-METIL-PROPIL)-FENOL, ENTRE OTROS Y B) UN ANTAGONISTA DEL RECEPTOR N-METIL-D-ASPARTATO (NMDA) TAL COMO (R,S)-QUETAMINA, (S)-QUETAMINA, MEMANTINA, NORVALINA, ENTRE OTROS. DICHA COMPOSICION FARMACEUTICA ES UTIL EN EL TRATAMIENTO DEL DOLOR Y PRESENTA UN EFECTO SINERGICO