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COMPOSITIONS AND METHODS OF USE FOR AUGMENTED IMMUNE RESPONSE, AND CANCER THERAPY
专利权人:
发明人:
KNEE DEBORAH A,BROGDON JENNIFER,WANG FEI
申请号:
IN3196/DEL/2015
公开号:
IN2015DE03196A
申请日:
2015.10.06
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present invention provides antibody compositions, including, e.g., antibodies, engineered antibodies and antibody fragments that bind to a tumor necrosis factor receptor superfamily member (i.e., 18). Provided compositions are useful in enhancing CD4+ and CD8+ T cell responses, and in the treatment, amelioration and prevention of diseases that can be counteracted with an augmented immune response, e.g., cancers. Also provided in the invention are polynucleotides and vectors that encode such molecules and host cells that harbor the polynucleotides or vectors as well as pharmaceutical compositions that comprise such molecules and methods of use thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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